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Laziness
Beginning of paper
Keratinization, absence of granular layer, and depositation of antibodies
and complement components in the stratum corneum. Most notable is the
hyperproliferation of keratinocytes in the epidermis. These keratinocytes
exhibit an increased mitotic rate and have ten times the turnover rate of
normal keratinocytes. There is also an infiltra .... Middle of paper
.... occur in advancing lesions before the
accumulation of inflammatory cells. These changes are mediated by
activated CD4+ T lymphocytes and can be detected before visible pathology
to the skin occurs. Activated T lymphocytes exhibiting an increase in
HLA-DR and IL-2R can be seen in close proximity to Langerhans cells in the
dermis before lesion formation. Since Langerhans cells are antigen
presenting cells, activation of the T cells may occur ....
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Number of words: 1951
Number of pages: 8 (approx. 250 words per double-spaced page)
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